Within these cells, AAS can biotransform into distinct metabolites or bind for their cognate receptor: the androgen receptor. AAS and their metabolites can cause side effects such as acne vulgaris, hypertension, hepatotoxicity, dyslipidemia, testosterone deficiency, erectile dysfunction, gynecomastia, and cardiomyopathy. Wherever applicable, we poi

AASs exert their effects by activating androgen receptor (AR) signaling. Numerous parts of your body are involved because of the presence of ARs in several tissues [twelve]. At standard physiologic amounts of testosterone androgen receptors are saturated and the AASs effects could be a consequence of other mechanisms rather then androgen receptors

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